Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021-Reference-Cited by-同舟云学术

Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021

Published:2022-03-17 Issue:11 Volume:27 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Blomquist Paula B¹^ORCID,Bridgen Jessica¹^ORCID,Bray Neil¹,O’Connell Anne Marie¹,West Daniel²,Groves Natalie²^ORCID,Gallagher Eileen²,Utsi Lara¹^ORCID,Jarvis Christopher I³¹^ORCID,Hardstaff Jo L¹^ORCID,Byers Chloe¹^ORCID,Metelmann Soeren¹^ORCID,Simons David¹^ORCID,Zaidi Asad²^ORCID,Twohig Katherine A²^ORCID,Savagar Bethan¹,Løchen Alessandra¹^ORCID,Ryan Cian¹^ORCID,Wrenn Katie¹,Saavedra-Campos María¹^ORCID,Abedin Zahidul¹^ORCID,Florence Isaac²^ORCID,Cleary Paul¹^ORCID,Elson Richard⁴¹^ORCID,Vivancos Roberto¹^ORCID,Lake Iain R⁴¹^ORCID

Affiliation:

1. COVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom

2. UK Health Security Agency, London, United Kingdom

3. London School of Hygiene and Tropical Medicine, London, United Kingdom

4. School of Environmental Sciences, UEA, Norwich, United Kingdom

Abstract

When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference17 articles.

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