Humoral immune escape by current SARS-CoV-2 variants BA.2.86 and JN.1, December 2023-Reference-Cited by-同舟云学术

Humoral immune escape by current SARS-CoV-2 variants BA.2.86 and JN.1, December 2023

Published:2024-01-11 Issue:2 Volume:29 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Jeworowski Lara M¹²,Mühlemann Barbara¹³²,Walper Felix²,Schmidt Marie L²,Jansen Jenny²,Krumbholz Andi⁴⁵,Simon-Lorière Etienne⁶⁷,Jones Terry C⁸³²,Corman Victor M⁹¹⁰³²,Drosten Christian⁹³²

Affiliation:

1. These authors contributed equally to the work and share the first authorship.

2. Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany

3. German Centre for Infection Research (DZIF), partner site Charité, Berlin, Germany

4. Laboratory Dr. Krause und Kollegen MVZ GmbH, Kiel, Germany

5. Institute for Infection Medicine, Christian-Albrechts-Universität zu Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany

6. National Reference Center for Viruses of Respiratory Infections, Institut Pasteur, Paris, France

7. G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris Cité, Paris, France

8. Centre for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, United Kingdom

9. These authors contributed equally to the work and share the last authorship.

10. Labor Berlin - Charité Vivantes GmbH, Berlin, Germany

Abstract

Variant BA.2.86 and its descendant, JN.1, of SARS-CoV-2 are rising in incidence across Europe and globally. We isolated recent JN.1, BA.2.86, EG.5, XBB.1.5 and earlier variants. We tested live virus neutralisation of sera taken in September 2023 from vaccinated and exposed healthy persons (n = 39). We found clear neutralisation escape against recent variants but no specific pronounced escape for BA.2.86 or JN.1. Neutralisation escape corresponds to recent variant predominance but may not be causative of the recent upsurge in JN.1 incidence.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference24 articles.

1. Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa.;Tegally;Nat Med,2022

2. Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86 lineages combining increased fitness and antibody evasion.;Planas;bioRxiv,2023

3. Antigenicity and infectivity characterisation of SARS-CoV-2 BA.2.86.;Yang;Lancet Infect Dis,2023

4. Neutralization escape by SARS-CoV-2 Omicron subvariant BA.2.86.;Lasrado;Vaccine,2023

5. Sensitivity of the SARS-CoV-2 BA.2.86 variant to prevailing neutralising antibody responses.;Sheward;Lancet Infect Dis,2023

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Where are we now?;Eurosurveillance;2024-01-11

2. Evaluation of the cross reactivity of neutralising antibody response in vaccinated human and convalescent hamster sera against SARS-CoV-2 variants up to and including JN.1 using an authentic virus neutralisation assay;2023-10-23