Investigation of an imported case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Florence, Italy, May to June 2013

Author:

Puzelli S1,Azzi A2,Santini M G3,Di Martino A1,Facchini M1,Castrucci M R1,Meola M1,Arvia R2,Corcioli F2,Pierucci F2,Baretti S3,Bartoloni A4,Bartolozzi D5,de Martino M6,Galli L6,Pompa M G7,Rezza G1,Balocchini E8,Donatelli I1

Affiliation:

1. National Influenza Centre, Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore Sanità (ISS), Rome, Italy

2. Regional reference laboratory for Influenza, Department of Experimental and Clinical Medicine, University of Florence, Italy

3. Local health district (ASL 10), Florence, Italy

4. Infectious and Tropical Diseases Unit, Careggi Hospital, Florence, Italy

5. Infectious Diseases Unit, Careggi Hospital, Florence, Italy

6. Department of Health Sciences, University of Florence, Anna Meyer University Children's Hospital, Florence, Italy

7. Ministry of Health, Rome, Italy

8. Tuscany Regional Health Authority, Florence, Italy

Abstract

On 31 May 2013, the first case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Italy was laboratory confirmed in a previously healthy adult man, who developed pneumonia with moderate respiratory distress after returning from a holiday in Jordan. Two secondary cases were identified through contact tracing, among family members and colleagues who had not previously travelled abroad. Both secondary cases developed mild illness. All three patients recovered fully.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference13 articles.

1. Corman VM, Eckerle I, Bleicker T, Zaki A, Landt O, Eschbach-Bludau M, et al. Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction. Euro Surveill. 2012;17(39):pii=20285. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20285

2. Public Health England (PHE). Infection control advice. Middle East respiratory syndrome coronavirus. Infection control advice: possible or confirmed MERS-CoV cases: Version 2.0, 28 June 2013. London: PHE; 2013. Available from: http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1317136232722

3. The Health Protection Agency (HPA) UK Novel Coronavirus Investigation team. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill. 2013;18(11):pii=20427. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20427

4. World Health Organization (WHO). Laboratory testing for novel coronavirus. Interim recommendations. 21 December 2012. Geneva: WHO; 2012. Available from: http://www.who.int/csr/disease/coronavirus_infections/LaboratoryTestingNovelCoronavirus_21Dec12.pdf

5. European Centre for Disease Prevention and Control (ECDC). Severe respiratory disease associated with Middle East respiratory syndrome coronavirus (MERS-CoV). 17 May 2013. Stockholm: ECDC; 17 May 2013. Available from: http://www.ecdc.europa.eu/en/publications/Publications/risk-assessment-middle-east-respiratory-syndrome-coronavirus-MERS-CoV-17-may-2013.pdf

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