1. Department of Cellular and Molecular Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, U.K.
2. Wolfson Institute for Biomedical Research, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, U.K.
3. Centre for Clinical Pharmacology, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, U.K.