Interferon regulatory factor 1 inactivation in human cancer-Reference-Cited by-同舟云学术

Interferon regulatory factor 1 inactivation in human cancer

Published:2018-05-08 Issue:3 Volume:38 Page:
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Alsamman Khaldoon¹,El-Masry Omar S.¹

Affiliation:

1. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia

Abstract

Interferon regulatory factors (IRFs) are a group of closely related proteins collectively referred to as the IRF family. Members of this family were originally recognized for their roles in inflammatory responses; however, recent research has suggested that they are also involved in tumor biology. This review focusses on current knowledge of the roles of IRF-1 and IRF-2 in human cancer, with particular attention paid to the impact of IRF-1 inactivation. The different mechanisms underlying IRF-1 inactivation and their implications for human cancers and the potential importance of IRF-1 in immunotherapy are also summarized.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/doi/10.1042/BSR20171672/808035/bsr-2017-1672.pdf

Reference122 articles.

1. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements;Miyamoto;Cell,1988

2. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes;Harada;Cell,1989

3. Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors;Meraro;J. Immunol.,1999

4. IRF family of transcription factors as regulators of host defense;Taniguchi;Annu. Rev. Immunol.,2001

5. The IRF family of transcription factors: Inception, impact and implications in oncogenesis;Yanai;Oncoimmunology,2012

Cited by 65 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens;2024-01-30

2. Low-dose radiotherapy encourages the generation of IFN and improves the tumor immune microenvironment;2024-01-30

3. Low-dose radiotherapy encourages the generation of IFN and improves the tumor immune microenvironment;2024-01-30

4. Molecular Atlas of HER2+ Breast Cancer Cells Treated with Endogenous Ligands: Temporal Insights into Mechanisms of Trastuzumab Resistance;Cancers;2024-01-27

5. Interferon‐regulatory factor‐1 boosts bevacizumab cardiotoxicity by the vascular endothelial growth factor A/14‐3‐3γ axis;ESC Heart Failure;2024-01-17