In-Hospital Mortality in Hyponatremia Patients Hospitalized for Heart Failure at National Institute of Cardiovascular Disease (N.I.C.V.D) Karachi

Abstract

Heart failure is a clinical syndrome that appears when the heart either is unable to sustain a sufficient cardiac output or can only do so at the cost of an increased filling pressure. Hyponatremia is poor prognostic sign. Objective: To determine the frequency of in-hospital mortality in hyponatremic patients hospitalized for heart failure at National Institute of Cardiovascular Disease (N.I.C.V.D) Karachi. Methods: This cross sectional study was conducted at Department of Cardiology, NICVD, Karachi, Pakistan from 1st March 2018 to 31st August 2018. All patient who fulfilled the inclusion criteria were enrolled and consent was taken. All the patients were managed according to guidelines and followed during hospital stay for in-hospital mortality. Data were collected in proforma. Results: The in-hospital mortality was 13(9.09%). Lower admission serum sodium was associated with high mortality. Conclusions: Patients hospitalized with  heart failure frequently had hyponatremia, which was linked to greater in-hospital mortality. Severe hyponatremic patients have worse clinical outcomes