Strategy for Procalcitonin-Controlled Antimicrobial Therapy in the COVID-19 Pandemic

Author:

Zaytsev A. A.1ORCID,Dronov I. A.2,Kondratieva T. V.3ORCID

Affiliation:

1. Burdenko Main Military Clinical Hospital; Medical Institute of Continuing Education

2. Sechenov First Moscow State Medical University (Sechenov University)

3. The 1586th Military Clinical Hospital

Abstract

The objective of this review is to optimize the use of antibiotic therapy for COVID-19 based on the published and our own data. The decision to prescribe antibiotic therapy in case of secondary bacterial pneumonia associated with SARS-CoV-2 should be based on a comprehensive assessment of the results of clinical, laboratory and instrumental examination including the elevated level of procalcitonin (more than 0,5 ng/ml).To achieve this objective, 48 publications were analyzed.

Publisher

LLC "Medical Knowledge and Technologies"

Subject

General Medicine

Reference48 articles.

1. Avdeev S.A., Dekhnich A.V., Zaytsev A.A., Sinopalnikov A.I., Kozlov R.S. et al. Vnebolnichnaya pnevmoniya u vzroslykh. Klinicheskiye rekomendatsii RRO i MAKMAKH, 2021. [Community-acquired pneumonia in adults. Clinical guidelines by RRS and IACMAC, 2021]. (Epub.), Available at: https://www.antibiotic.ru/files/306/kr654.pdf.

2. Vremennye metodicheskie rekomendatsii. Profilaktika, diagnostika i lechenie novoy koronavirusnoy infektsii (COVID-19) Versiya 15. 22.02.2022. [Provisional guidelines on prevention, diagnostics and treatment of the new coronavirus infection (COVID-19). Version 15. February 02, 2022]. (Epub.), Available at: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/059/392/original/ВМР_COVID-19_V15.pdf.

3. Zaytsev A.A. Correspondence column. Klinicheskaya Mikrobiologiya i Antimikrobnaya Khimioterapiya, 2020, vol. 22, no. 2, pp. 84-86. (In Russ.) doi: 10.36488/cmac.2020.2.84-86.

4. Zaytsev A.A., Golukhova E.Z., Mamaliga M.L., Chernov S.A., Rybka M.M., Kryukov E.V., Klyuchnikov I.V., Semenov V.Yu., Orlov I.N. Efficacy of methylprednisolone pulse therapy in patients with COVID-19. Klinicheskaya Mikrobiologiya i Antimikrobnaya Khimioterapiya, 2020, vol. 22, no. 2, pp. 88-91. (In Russ.) doi: 10.36488/cmac.2020.2.88-91.

5. Zaytsev A.A., Ovchinnikov Yu.V., Kondratieva T.V. An analysis of diagnostic values of prognostic tools for community-acquired pneumonia in young patients in a closed community. Pulmonologiya, 2014, no. 5, pp. 67-72. (In Russ.) https://doi.org/10.18093/0869-0189-2014-0-5-67-72.

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