Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial-Reference-Cited by-同舟云学术

Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial

Published:2024-10-01 Issue:10 Volume:178 Page:976
ISSN:2168-6203
Container-title:JAMA Pediatrics
language:en
Short-container-title:JAMA Pediatr

Author:

Merhar Stephanie L.¹²,Hu Zhuopei³,Devlin Lori A.⁴,Ounpraseuth Songthip T.³,Simon Alan E.⁵⁶,Smith P. Brian⁷,Walsh Michele C.⁸,Lee Jeannette Y.³,Das Abhik⁹,Higgins Rosemary D.¹⁰,Crawford Margaret M.⁹,Rice Ward¹²¹¹,Paul David A.¹²,Maxwell Jessie R.¹³,Telang Sucheta D.⁴,Fung Camille M.¹⁴,Wright Tanner¹⁵,Reynolds Anne-Marie¹⁶,Hahn Devon¹⁷,Ross Julie¹⁸,McAllister Jennifer M.¹,Crowley Moira¹⁹,Shaikh Sophie K.²⁰,Christ Lori²¹,Brown Jaime²²,Riccio Julie²³,Wong Ramsey Kara²⁴,Braswell Erica F.²⁵,Tucker Lauren²⁶,McAlmon Karen²⁷,Dummula Krishna²⁸,Weiner Julie²⁹,White Jessica R.³⁰,Howell Meghan P.³¹,Newman Sarah³²,Snowden Jessica N.³³,Young Leslie W.³⁴, ,Hubberd De Ann³⁵,Edwards Kathy³⁵,Whalen Bonny L.³⁵,MacMillan Kate³⁵,Pahl Adrienne³⁵,Sheehan Desselle Farrah³⁵,White Katie³⁵,Hibbs Anna Marie³⁵,Clarke Leslie³⁵,Serio Kathy³⁵,Kertesz Maria³⁵,Rodriguez Ashley³⁵,Driscoll Sarah³⁵,Hammond Kim³⁵,Hines Deborah³⁵,Kish Patricia³⁵,Schmidt Taylor³⁵,Stepp Jennifer³⁵,Jackson Jodi³⁵,Scott Allie³⁵,Brown Rochelle³⁵,Smith Kari³⁵,Rieper My³⁵,Miner Carrie³⁵,Ray Lynne³⁵,Kowel Karen³⁵,Reynolds Victoria³⁵,Castellone Diana³⁵,Mackley Amy³⁵,Schibler Kurt³⁵,Beiersdorfer Traci³⁵,Grisby Cathy³⁵,Kirker Kristin³⁵,McKeown Katherine³⁵,Loudermilk M. Katherine³⁵,Carnohan Amy³⁵,Froese Patti³⁵,Haddix April³⁵,Summe Virginia³⁵,Chlon Clara³⁵,Kunk Rita³⁵,Hamilton Jen³⁵,Moore Sadie³⁵,Ziegelmeyer Angela³⁵,Rolfes Lucy³⁵,Schomaker Erica³⁵,Strike Holly³⁵,Harvey Sharon³⁵,Richards Paula³⁵,Simon Ashley³⁵,Russell David³⁵,Gleason Christine A.³⁵,Allen Marilee C.³⁵,Boyle Robert J.³⁵,Clemons Traci³⁵,D’Alton Mary E.³⁵,Steinhorn Robin³⁵,Weiner Steven J.³⁵,Blaisdell Carol J.³⁵,Wilson Archer Stephanie³⁵,Amiotte Annette³⁵,Santos Moara³⁵,Taosaka Jill³⁵,Neal Charles³⁵,Atz Andrew M.³⁵,Summer Andrea³⁵,Amaya Michelle³⁵,Freeman Mary³⁵,Johnson Madison³⁵,Sarraf Layla Al³⁵,Ros-Demarize Rosemary³⁵,Sánchez Pablo J.³⁵,Slaughter Jonathan L.³⁵,Benninger Kristen³⁵,Luzader Patricia³⁵,Marzec Laura³⁵,DeSantis Brittany³⁵,Small Kristi³⁵,Newton Julia³⁵,Purnell Jessica³⁵,Reedy Rachel³⁵,Hanlon Cory³⁵,Naik Tanvi³⁵,Knox Jordan³⁵,Tallikar Aishwarya³⁵,Cobe Chelsea³⁵,Resetar Megan³⁵,McCool Jacqueline³⁵,Frailey Erin³⁵,Jones Stephanie³⁵,Williams Stacy³⁵,Staton Taise³⁵,Palmer Jacqueline N.³⁵,Erner Jana L.³⁵,Kovalcik Jason B.³⁵,Keels Erin L.³⁵,McCarty Teri³⁵,Harris Katherine³⁵,DeSpain Meagan³⁵,Boyd Jackie³⁵,Watson Sara³⁵,Sullivan Jan³⁵,Walsh Timothy³⁵,Anderson Brianna³⁵,Hahn Devon³⁵,Madden Christi³⁵,Nascimbeni Anne³⁵,Wilson Shannon³⁵,Gibson Theresa³⁵,Karlin John³⁵,Bann Carla M.³⁵,O’Donnell Auman Jeanette³⁵,Turner Eugene³⁵,Smith Emily³⁵,Bradley Lauren³⁵,Trochinski Lillian³⁵,Gabrio Jenna³⁵,Leblond David³⁵,Pickett James³⁵,Newman Jamie E.³⁵,Zaterka-Baxter Kristin M.³⁵,Baack Michelle L.³⁵,Hogden Laurie A.³⁵,Elenkiwich Chelsey³⁵,Henning Megan M.³⁵,Van Muyden Sarah³⁵,Martino Anna-Lisa³⁵,Lutz Allison³⁵,Nelson Jeralyn³⁵,Schumacher Bette³⁵,Brodkorb Aimee³⁵,Pritchett Deborah³⁵,Ford Kristen³⁵,Howard Darla³⁵,Orland Ryan³⁵,Diles Monique³⁵,Shuttleworth Kay L.³⁵,Hubberd DeAnn E.³⁵,Edwards Kathy D.³⁵,Lloyd Sherry L.³⁵,Banks-Johnson Catrice³⁵,Robinson Patrina³⁵,Griffith Melissa³⁵,Slaughter Amie³⁵,Kilkenny Teresa³⁵,Foster Kristina³⁵,Cross Morgan³⁵,Gier Jessica³⁵,Roberts Natalie³⁵,Wadman Jessica³⁵,Cathey Kathy³⁵,Todd Jenna³⁵,Fratesi Emily³⁵,Malloch Lacy³⁵,Alur Radha³⁵,Majure Joseph Marc³⁵,Walker Courtney³⁵,Powers Catherine³⁵,Annett Robert D.³⁵,Wellman Rachel³⁵,Miller Kerry³⁵,Anderson-Berry Ann³⁵,Raissy Hengameh³⁵,Kong Alberta³⁵,McCalmont Kate³⁵,Sundquist Beauman Sandra³⁵,Sanders Sarah³⁵,Eichenwald Eric C.³⁵,Mancini Toni³⁵,Ziolkowski Kristina³⁵,Dhawan Megan³⁵,Gambacorta Mary Kay³⁵,Pulsifer Allie³⁵,Brant Marisa³⁵,Schumacher Aida³⁵,Gocial Sydney³⁵,Azuma Kristen³⁵,Quigley Elizabeth³⁵,Zachritz Whitney³⁵,Pastore Nicole³⁵,Barber Jessica³⁵,McDowell Abby³⁵,Ferri Alissa³⁵,Parga-Belinkie Joanna³⁵,Guillet Ronnie³⁵,Jensen Rosemary L.³⁵,Kent Alison³⁵,Scorsone Ann Marie³⁵,Lakshminrusimha Satyan³⁵,Hartley-McAndrews Michelle E.³⁵,Li Emily³⁵,Donato Jennifer³⁵,McKee Kimberly G.³⁵,D’Angio Carl³⁵,Jones Rachel³⁵,Terrano Dacia³⁵,Solpietro Stephanie³⁵,Brei Lisa³⁵,Krokovich Lisa³⁵,Hart Sema³⁵,Pastore John³⁵,Kern Ashley³⁵,Mars Margaret³⁵,Volker Patricia³⁵,Mioneo Brady Annette³⁵,Voelker Kelsey³⁵,Horn Emily³⁵,Moreland Melissa³⁵,Kneusel Marcia³⁵,Balakrishnan Maya³⁵,Childres Jillian³⁵,Hanniman Melissa³⁵,White Rebecca³⁵,Ohls Robin K.³⁵,Baserga Mariana³⁵,Muniyappa Bhanu³⁵,Shakib Julie³⁵,Rau Carrie A.³⁵,Baker Shawna³⁵,Coleman Kathie³⁵,McGrath Kandace M.³⁵,Petersen Brandy³⁵,Waldvogel Jael³⁵,Bracken Monika³⁵,Ferrin Meredith³⁵,DeSantis Holly³⁵,Perkins Traci³⁵,Loertscher Manndi C.³⁵,McAlmon Karen³⁵,Goldstein Justin³⁵,Angelidou Asimenia³⁵,Donahue Nancy³⁵

Affiliation:

1. Perinatal Institute, Division of Neonatology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio

2. Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio

3. Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock

4. Department of Pediatrics, University of Louisville, Louisville, Kentucky

5. Institutional Development Awards States Pediatric Clinical Trials Network, Environmental Influences on Child Health Outcomes Program, National Institutes of Health, Rockville, Maryland

6. Now with the National Center for Health Statistics, US Centers for Disease Control and Prevention, Rockville, Maryland

7. Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina

8. Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland

9. Social, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, North Carolina

10. Office of Research and Sponsored Programs, Florida Gulf Coast University, Fort Myers

11. St Elizabeth Healthcare, Edgewood, Kentucky

12. Division of Neonatology, Department of Pediatrics, ChristianaCare, Newark, Delaware

13. University of New Mexico School of Medicine, Albuquerque

14. Department of Pediatrics, Division of Neonatology, University of Utah School of Medicine, Salt Lake City

15. Department of Pediatrics, University of South Florida, Tampa

16. Department of Pediatrics, University at Buffalo, Buffalo, New York

17. Oklahoma University Health Sciences Center, Oklahoma City

18. Medical University of South Carolina, Health Shawn Jenkins Children’s Hospital, Charleston

19. Department of Pediatrics, Rainbow Babies & Children’s Hospital, Case Western Reserve University, Cleveland, Ohio

20. Department of Pediatrics, Duke University, Durham, North Carolina

21. Hospital of the University of Pennsylvania, Philadelphia

22. Department of Pediatrics, Spartanburg Regional Medical Center, Spartanburg, South Carolina

23. University of Rochester School of Medicine and Dentistry, Rochester, New York

24. Kapiʻolani Medical Center for Women & Children, Honolulu, Hawaii

25. Department of Pediatrics, Nationwide Children’s Hospital, The Ohio State University College of Medicine, Columbus

26. Department of Pediatrics, University of Mississippi Medical Center, Jackson

27. Winchester Hospital, Winchester, Massachusetts

28. Department of Pediatrics, University of Kansas Medical Center, Kansas City, Missouri

29. Children’s Mercy, Kansas City, Missouri

30. Sanford Health, Sioux Falls, South Dakota

31. Tulane University School of Medicine, New Orleans, Louisiana

32. University of Nebraska Medical Center, Omaha

33. Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock

34. Larner College of Medicine at the University of Vermont, Burlington

35. for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network National Institutes of Health Environmental Influences on Child Health Outcomes Program Institutional Development Award States Pediatric Clinical Trials Network

Abstract

ImportanceInfants with neonatal opioid withdrawal syndrome (NOWS) cared for with the Eat, Sleep, Console (ESC) care approach receive less pharmacologic treatment and have shorter hospital stays compared to usual care with the Finnegan Neonatal Abstinence Scoring Tool, but the effects of these approaches on feeding and weight are unknown.ObjectiveTo evaluate feeding practices and weight trajectories in infants cared for with ESC vs usual care.Design, Setting, and ParticipantsESC-NOW is a cluster randomized trial of infants with NOWS born at 36 weeks’ gestation or later at 26 US hospitals from September 2020 to March 2022. Each site transitioned from usual care to ESC (the study intervention) at a randomized time. Feeding was per site practice and not specified by the intervention. Feeding and weight outcomes were assessed at hospital discharge.InterventionESC vs usual care.Main Outcomes and MeasuresOutcomes include prospectively identified secondary end points related to feeding and weight. z Scores were used for growth to account for corrected gestational age at the time of measurement. All analyses were intention to treat and adjusted for study design. Maternal/infant characteristics were included in adjusted models.ResultsThe analyses included 1305 infants (702 in usual care and 603 in ESC; mean [SD] gestational age, 38.6 [1.3] weeks; 655 [50.2%] male and 650 [49.8%] female). Baseline demographic characteristics were similar between groups. The proportion of breastfed infants was higher in the ESC group (52.7% vs 41.7%; absolute difference, 11%; 95% CI, 1.0-20.9). A higher proportion of infants cared for with ESC received exclusive breast milk (15.1% vs 6.7%; absolute difference, 8.4%; 95% CI, 0.9-5.8) or any breast milk (38.8% vs 27.4%; absolute difference, 11.4%; 95% CI, 0.2-23.1) and were directly breastfeeding at discharge (35.2% vs 19.5%; absolute difference, 15.7%; 95% CI, 4.1-27.3). There was no difference in proportion of infants with weight loss greater than 10% or maximum percentage weight loss, although infants cared for with ESC had a lower weight z score on day of life 3 (−1.08 vs −1.01; absolute difference, 0.07; 95% CI, 0.02-0.12). When pharmacologic treatment was added into the model, no breastfeeding outcomes were statistically significant.Conclusions and RelevanceIn this study, infants cared for with ESC were more likely to initiate and continue breastfeeding and had no difference in percentage weight loss. The improvement in breastfeeding with ESC may be driven by reduction in pharmacologic treatment and provision of effective nonpharmacologic care.Trial RegistrationClinicalTrials.gov Identifier: NCT04057820

Publisher

American Medical Association (AMA)

Link

https://jamanetwork.com/journals/jamapediatrics/articlepdf/2822088/jamapediatrics_merhar_2024_oi_240044_1728048808.8789.pdf

Reference23 articles.

1. Patterns of disruptive feeding behaviors in infants with neonatal abstinence syndrome.;Maguire;Adv Neonatal Care,2015

2. Feeding infants with neonatal abstinence syndrome: finding the sweet spot.;Maguire;Neonatal Netw,2018

3. Postnatal weight loss in substitute methadone-exposed infants: implications for the management of breast feeding.;Dryden;Arch Dis Child Fetal Neonatal Ed,2012

4. Breastfeeding rates among mothers of infants with neonatal abstinence syndrome.;Wachman;Breastfeed Med,2010

5. An initiative to improve the quality of care of infants with neonatal abstinence syndrome.;Grossman;Pediatrics,2017

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