<i>MT-RNR1</i> Genotype Should Not Affect Childhood Vaccination—Unintended Consequences of Guidelines-Reference-Cited by-同舟云学术

MT-RNR1 Genotype Should Not Affect Childhood Vaccination—Unintended Consequences of Guidelines

Published:2023-11-01 Issue:11 Volume:177 Page:1119
ISSN:2168-6203
Container-title:JAMA Pediatrics
language:en
Short-container-title:JAMA Pediatr

Author:

McDermott John H.¹²,Wolf Joshua³,Newman William G.¹²

Affiliation:

1. Manchester Centre for Genomic Medicine, St Mary’s Hospital, Manchester University NHS Foundation Trust, Manchester, United Kingdom

2. Division of Evolution, Infection and Genomic Sciences, School of Biological Sciences, University of Manchester, Manchester, United Kingdom

3. Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee

Abstract

This Viewpoint discusses whether routine vaccination is safe for children with MT-RNR1 gene variants that predispose to aminoglycoside-induced hearing loss.

Publisher

American Medical Association (AMA)

Subject

Pediatrics, Perinatology and Child Health

Link

https://jamanetwork.com/journals/jamapediatrics/articlepdf/2808912/jamapediatrics_mcdermott_2023_vp_230025_1698695736.48131.pdf

Reference8 articles.

1. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for the use of aminoglycosides based on MT-RNR1 genotype.;McDermott;Clin Pharmacol Ther,2022

2. Rapid point-of-care genotyping to avoid aminoglycoside-induced ototoxicity in neonatal intensive care.;McDermott;JAMA Pediatr,2022

3. Adverse effects of a single dose of gentamicin in adults: a systematic review.;Hayward;Br J Clin Pharmacol,2018

4. High-dose gentamicin in newborn infants: is it safe?;Fjalstad;Eur J Pediatr,2013

5. Temporal associations between immunization with the COVID-19 mRNA vaccines and myocarditis: the vaccine safety surveillance system is working.;Navar;JAMA Cardiol,2021