1. Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany2Center for Sepsis Control & Care, Jena University Hospital, Jena, Germany
2. Clinical Trial Centre Leipzig, University of Leipzig, Leipzig, Germany
3. Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany
4. Department of Anesthesiology, University Hospital Munich, Munich, Germany
5. Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada
6. Department of Anesthesiology and Surgical Intensive Care Medicine, Hospital Augsburg, Augsburg, Germany
7. Department of Anesthesiology, University Hospital Göttingen, Göttingen, Germany
8. Department of Anesthesiology and Intensive Care Medicine, University Hospital Oldenburg, Oldenburg, Germany
9. Department of Intensive Care Medicine, University Hospital Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany
10. Department of Anesthesiology and Intensive Care Medicine, University Hospital Greifswald, Germany
11. Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany
12. Department of Nephrology and Intensive Care Medicine, Charité Berlin, Berlin, Germany
13. Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, HELIOS Hospital Erfurt, Erfurt, Germany
14. Department of General Surgery, University Hospital Freiburg, Freiburg, Germany
15. Department of Anesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany
16. Department of Anesthesiology and Surgical Intensive Care Medicine, University Hospital Bonn, Bonn, Germany
17. Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany
18. Department of Anesthesiology and Intensive Care Medicine, University Hospital Dresden, Dresden, Germany
19. Department of Anesthesiology, Surgical Intensive Care Medicine and Pain Therapy, Vivantes Hospital Neukölln, Berlin, Germany
20. Institute for Clinical Chemistry, Jena University Hospital, Jena, Germany
21. Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany
22. Clinical Trial Centre Leipzig, University of Leipzig, Leipzig, Germany22Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany