Effect of a Lower vs Higher Positive End-Expiratory Pressure Strategy on Ventilator-Free Days in ICU Patients Without ARDS

Author:

,Algera Anna Geke1,Pisani Luigi1,Serpa Neto Ary234,den Boer Sylvia S.5,Bosch Frank F. H.6,Bruin Karina7,Klooster Pauline M.8,Van der Meer Nardo J. M.9,Nowitzky Ralph O.10,Purmer Ilse M.10,Slabbekoorn Mathilde8,Spronk Peter E.11,van Vliet Jan6,Weenink Jan J.5,Gama de Abreu Marcelo12,Pelosi Paolo13,Schultz Marcus J.11415,Paulus Frederique116

Affiliation:

1. Department of Intensive Care and Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam UMC, Location AMC, Amsterdam, the Netherlands

2. Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil

3. Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Victoria, Australia

4. Data Analytics Research and Evaluation (DARE) Centre, Austin Hospital and University of Melbourne, Melbourne, Victoria, Australia

5. Department of Intensive Care, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands

6. Department of Intensive Care, Rijnstate Hospital, Arnhem, the Netherlands

7. Department of Intensive Care, Westfriesgasthuis, Hoorn, the Netherlands

8. Department of Intensive Care, Haaglanden MC, the Hague, the Netherlands

9. Department of Intensive Care, Amphia Hospital, Breda, the Netherlands

10. Department of Intensive Care, Haga Hospital, the Hague, the Netherlands

11. Department of Intensive Care, Gelre Hospitals, Apeldoorn, the Netherlands

12. Department of Anesthesiology and Intensive Care, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Dresden, Germany

13. Department of Surgical Sciences and Integrated Diagnostics, San Martino Policlinico Hospital, IRCCS for Oncology, University of Genoa, Genoa, Italy

14. Nuffield Department of Medicine, Oxford University, Oxford, England

15. Mahidol-Oxford Tropical Medicine Research Unit (MORU), Mahidol University, Bangkok, Thailand

16. ACHIEVE Centre of Expertise, Faculty of Health, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands

Publisher

American Medical Association (AMA)

Subject

General Medicine

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