Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury-Reference-Cited by-同舟云学术

Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury

Published:2020-09-08 Issue:10 Volume:324 Page:961
ISSN:0098-7484
Container-title:JAMA
language:en
Short-container-title:JAMA

Author:

Rowell Susan E.¹²,Meier Eric N.³,McKnight Barbara³,Kannas Delores³,May Susanne³,Sheehan Kellie³,Bulger Eileen M.⁴,Idris Ahamed H.⁵⁶,Christenson Jim⁷⁸,Morrison Laurie J.⁹¹⁰,Frascone Ralph J.¹¹,Bosarge Patrick L.¹²¹³,Colella M. Riccardo¹⁴,Johannigman Jay¹⁵,Cotton Bryan A.¹⁶,Callum Jeannie¹⁷,McMullan Jason¹⁸,Dries David J.¹⁹,Tibbs Brian²⁰,Richmond Neal J.²¹,Weisfeldt Myron L.²²,Tallon John M.⁷²³,Garrett John S.²⁴,Zielinski Martin D.²⁵,Aufderheide Tom P.¹⁴,Gandhi Rajesh R.²⁶,Schlamp Rob²³,Robinson Bryce R. H.⁴,Jui Jonathan²⁷,Klein Lauren²⁸,Rizoli Sandro²⁹,Gamber Mark³⁰,Fleming Michael¹,Hwang Jun³,Vincent Laura E.¹⁶,Williams Carolyn¹²,Hendrickson Audrey²⁸,Simonson Robert³¹,Klotz Patricia⁴,Sopko George³²,Witham William³³,Ferrara Michael²⁴,Schreiber Martin A.¹

Affiliation:

1. Department of Surgery, Oregon Health & Science University, Portland

2. Department of Surgery, Duke University School of Medicine, Durham, North Carolina

3. Department of Biostatistics, University of Washington, Seattle

4. Department of Surgery, University of Washington, Seattle

5. Department of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas

6. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas

7. Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada

8. Providence Health Care Research Institute, Vancouver, British Columbia, Canada

9. Rescu, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, Ontario, Canada

10. Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

11. Department of Emergency Medicine, Regions Hospital, St Paul, Minnesota

12. Department of Surgery, University of Alabama, Birmingham

13. Department of Surgery, University of Arizona, Phoenix

14. Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee

15. Department of Surgery, University of Cincinnati, Cincinnati, Ohio

16. Department of Surgery, McGovern Medical School, University of Texas Health Science Center, Houston

17. Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

18. Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio

19. Department of Surgery, Regions Hospital, St Paul, Minnesota

20. Trauma Surgery, Texas Health Presbyterian Hospital, Dallas

21. Department of Emergency Medicine, John Peter Smith Health Network, Ft Worth, Texas

22. Johns Hopkins School of Medicine, Baltimore, Maryland

23. British Columbia Emergency Health Services, Vancouver, British Columbia, Canada

24. Department of Emergency Medicine, Baylor University Medical Center, Dallas, Texas

25. Department of Surgery, Mayo Clinic, Rochester, Minnesota

26. Department of Surgery, John Peter Smith Health Network, Ft Worth, Texas

27. Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon

28. Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota

29. Department of Surgery, St Michael’s Hospital, Toronto, Ontario, Canada

30. Department of Emergency Medicine, Medical City Plano, Plano, Texas

31. Emergency Medicine, Methodist Dallas Medical Center, Dallas, Texas

32. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland

33. Trauma Surgery, Texas Health Harris Methodist Hospital, Ft Worth

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jama/articlepdf/2770409/jama_rowell_2020_oi_200057_1603742313.50665.pdf

Reference21 articles.

1. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.;Feigin;Lancet Neurol,2019

2. Corticosteroids for acute traumatic brain injury.;Alderson;Cochrane Database Syst Rev,2005

3. Hypothermia for traumatic brain injury.;Lewis;Cochrane Database Syst Rev,2017

4. Progesterone for acute traumatic brain injury.;Ma;Cochrane Database Syst Rev,2016

5. The effect of a new potent antifibrinolytic agent, tranexamic acid.;Kobayashi;J Jpn Obstet Gynecol Soc,1966

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