Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis-Reference-Cited by-同舟云学术

Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis

Published:2022-06-01 Issue:6 Volume:79 Page:575
ISSN:2168-6149
Container-title:JAMA Neurology
language:en
Short-container-title:JAMA Neurol

Author:

Oki Ryosuke¹,Izumi Yuishin¹,Fujita Koji¹,Miyamoto Ryosuke¹,Nodera Hiroyuki¹,Sato Yasutaka²,Sakaguchi Satoshi²,Nokihara Hiroshi²,Kanai Kazuaki³⁴,Tsunemi Taiji⁴,Hattori Nobutaka⁴,Hatanaka Yuki⁵,Sonoo Masahiro⁵,Atsuta Naoki⁶,Sobue Gen⁶,Shimizu Toshio⁷,Shibuya Kazumoto⁸,Ikeda Ken⁹,Kano Osamu⁹,Nishinaka Kazuto¹⁰,Kojima Yasuhiro¹¹,Oda Masaya¹²,Komai Kiyonobu¹³,Kikuchi Hitoshi¹⁴,Kohara Nobuo¹⁵,Urushitani Makoto¹⁶,Nakayama Yoshiaki¹⁷,Ito Hidefumi¹⁷,Nagai Makiko¹⁸,Nishiyama Kazutoshi¹⁸,Kuzume Daisuke¹⁹,Shimohama Shun²⁰,Shimohata Takayoshi²¹,Abe Koji²²,Ishihara Tomohiko²³,Onodera Osamu²³,Isose Sagiri²⁴,Araki Nobuyuki²⁴,Morita Mitsuya²⁵,Noda Kazuyuki²⁶,Toda Tatsushi²⁷,Maruyama Hirofumi²⁸,Furuya Hirokazu²⁹,Teramukai Satoshi³⁰,Kagimura Tatsuo³¹,Noma Kensuke³²³³,Yanagawa Hiroaki²,Kuwabara Satoshi⁸,Kaji Ryuji¹³⁴,Osaki Yusuke³⁵,Yamazaki Hiroki³⁵,Haji Shotaro³⁵,Ishida Yumi³⁵,Futami Akari³⁵,Miyamoto Toshiko³⁵,Akaishi Akiyo³⁵,Takechi Kenshi³⁵,Maeda Kazuki³⁵,Kurisu Shoko³⁵,Yoshizawa Mari³⁵,Matsuda Nozomu³⁵,Nakazato Tomoko³⁵,Nakamura Ryoichi³⁵,Hayashi Naoki³⁵,Kawata Akihiro³⁵,Kimura Hideki³⁵,Bokuda Kota³⁵,Tamura Akiko³⁵,Ishida Chiho³⁵,Kawamoto Michi³⁵,Kim Hyo³⁵,Kawamata Jun³⁵,Hisahara Shin³⁵,Kimura Yuichi³⁵,Yamashita Toru³⁵,Ohta Yasuyuki³⁵,Arai Kimihito³⁵,Takeda Takahiro³⁵,Ogawa Tomoo³⁵,Ikari Shingo³⁵,Ono Yasunori³⁵,Fujino Yukio³⁵,

Affiliation:

1. Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan

2. Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan

3. Department of Neurology, Fukushima Medical University School of Medicine, Fukushima, Japan

4. Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan

5. Department of Neurology, Teikyo University School of Medicine, Tokyo, Japan

6. Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan

7. Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan

8. Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan

9. Department of Neurology, Toho University Faculty of Medicine, Tokyo, Japan

10. Department of Neurology, Sumitomo Hospital, Osaka, Japan

11. Department of Neurology, Takeda General Hospital, Kyoto, Japan

12. Department of Neurology, Vihara Hananosato Hospital, Miyoshi, Japan

13. Department of Neurology, National Hospital Organization Iou Hospital, Kanazawa, Japan

14. Department of Neurology, Murakami Karindoh Hospital, Fukuoka, Japan

15. Department of Neurology, Kobe City Medical Center General Hospital, Kobe, Japan

16. Department of Neurology, Shiga University of Medical Science, Otsu, Japan

17. Department of Neurology, Wakayama Medical University, Wakayama, Japan

18. Department of Neurology, Kitasato University School of Medicine, Sagamihara, Japan

19. Department of Neurology, Chikamori Hospital, Kochi, Japan

20. Department of Neurology, Sapporo Medical University, Sapporo, Japan

21. Department of Neurology, Gifu University Graduate School of Medicine, Gifu, Japan

22. Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

23. Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan

24. Department of Neurology, National Hospital Organization Chibahigashi Hospital, Chiba, Japan

25. Division of Neurology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan

26. Department of Neurology, Juntendo University Shizuoka Hospital, Izunokuni, Japan

27. Department of Neurology, The University of Tokyo, Tokyo, Japan

28. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan

29. Department of Neurology, Kochi Medical School, Kochi University, Nankoku, Japan

30. Department of Biostatistics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

31. Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation, Kobe, Japan

32. Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan

33. Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan

34. Department of Neurology, National Hospital Organization Utano Hospital, Kyoto, Japan

35. for the Japan Early-Stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) Collaborators

Publisher

American Medical Association (AMA)

Subject

Neurology (clinical)

Link

https://jamanetwork.com/journals/jamaneurology/articlepdf/2792228/jamaneurology_oki_2022_oi_220017_1653667072.30456.pdf

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