Long-term Clinical Outcomes and Biomarker Analyses of Atezolizumab Therapy for Patients With Metastatic Triple-Negative Breast Cancer

Author:

Emens Leisha A.12,Cruz Cristina3,Eder Joseph Paul4,Braiteh Fadi5,Chung Cathie6,Tolaney Sara M.7,Kuter Irene8,Nanda Rita9,Cassier Philippe A.10,Delord Jean-Pierre11,Gordon Michael S.12,ElGabry Ehab13,Chang Ching-Wei14,Sarkar Indrani15,Grossman William1415,O’Hear Carol14,Fassò Marcella14,Molinero Luciana14,Schmid Peter16

Affiliation:

1. Bloomberg-Kimmel Institute for Cancer Immunotherapy, Department of Oncology, Johns Hopkins University, Baltimore, Maryland

2. now with Department of Medicine and UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh

3. Medical Oncology Department, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron University Hospital, Barcelona, Spain

4. Department of Medicine (Oncology), Yale Cancer Center, New Haven, Connecticut

5. Comprehensive Cancer Centers of Nevada, University of Nevada Las Vegas School of Medicine, Las Vegas

6. The Angeles Clinic and Research Institute, Los Angeles, California

7. Department of Medicine,Dana-Farber Cancer Institute, Boston, Massachusetts

8. Department of Medicine, Hematology/Oncology, Massachusetts General Hospital, Boston

9. Section of Hematology/Oncology, University of Chicago, Chicago, Illinois

10. Department of Medical Oncology, Centre Léon-Bérard, Lyon, France

11. Department of Medical Oncology, Institut Claudius Regaud, IUCT-Oncopole, Toulouse, France

12. HonorHealth Research Institute, Scottsdale, Arizona

13. Ventana Medical Systems, Inc, Tucson, Arizona

14. Genentech, Inc, South San Francisco, California

15. now with Bellicum Pharmaceuticals, Inc, South San Francisco, California

16. Centre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London, London, England

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference37 articles.

1. Triple-negative breast cancer: an unmet medical need.;Hudis;Oncologist,2011

2. Triple negative breast cancer—an overview.;Aysola;Hereditary Genet,2013

3. Triple-negative breast cancer has worse overall survival and cause-specific survival than non-triple-negative breast cancer.;Li;Breast Cancer Res Treat,2017

4. Survival with metastatic breast cancer based on initial presentation, de novo versus relapsed.;den Brok;Breast Cancer Res Treat,2017

5. Current approaches in treatment of triple-negative breast cancer.;Wahba;Cancer Biol Med,2015

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