Efficacy of Osimertinib Plus Bevacizumab vs Osimertinib in Patients With EGFR T790M–Mutated Non–Small Cell Lung Cancer Previously Treated With Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitor

Author:

Akamatsu Hiroaki1,Toi Yukihiro2,Hayashi Hidetoshi3,Fujimoto Daichi4,Tachihara Motoko5,Furuya Naoki6,Otani Sakiko7,Shimizu Junichi8,Katakami Nobuyuki9,Azuma Koichi10,Miura Naoko11,Nishino Kazumi12,Hara Satoshi13,Teraoka Shunsuke1,Morita Satoshi14,Nakagawa Kazuhiko3,Yamamoto Nobuyuki1

Affiliation:

1. Internal Medicine III, Wakayama Medical University, Wakayama, Japan

2. Department of Pulmonary Medicine, Sendai Kousei Hospital, Miyagi, Japan

3. Department of Medical Oncology, Faculty of Medicine, Kindai University, Osaka, Japan

4. Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Hyogo, Japan

5. Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan

6. Division of Respiratory Medicine, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa, Japan

7. Department of Respiratory Medicine, Kitasato University School of Medicine, Kanagawa, Japan

8. Department of Thoracic Oncology, Aichi Cancer Center Hospital, Aichi, Japan

9. Department of Medical Oncology, Department of Pulmonary Medicine, Chemotherapy Center and Division of Clinical Research, Takarazuka City Hospital, Hyogo, Japan

10. Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan

11. Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

12. Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan

13. Department of Respiratory Medicine, Itami City Hospital, Hyogo, Japan

14. Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

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