Evaluation of Plasma Microbial Cell-Free DNA Sequencing to Predict Bloodstream Infection in Pediatric Patients With Relapsed or Refractory Cancer

Author:

Goggin Kathryn P.1,Gonzalez-Pena Veronica2,Inaba Yuki2,Allison Kim J.1,Hong David K.3,Ahmed Asim A.3,Hollemon Desiree3,Natarajan Sivaraman2,Mahmud Ousman2,Kuenzinger William2,Youssef Sarah2,Brenner Abigail1,Maron Gabriela1,Choi John4,Rubnitz Jeffrey E.25,Sun Yilun6,Tang Li6,Wolf Joshua157,Gawad Charles258

Affiliation:

1. Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee

2. Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee

3. Karius Inc, Redwood City, California

4. Department of Pathology, St Jude Children's Research Hospital, Memphis, Tennessee

5. Department of Pediatrics, The University of Tennessee Health Science Center, Memphis

6. Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee

7. Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia

8. Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference15 articles.

1. Catheter-associated bloodstream infections in pediatric hematology-oncology patients: factors associated with catheter removal and recurrence.;Adler;J Pediatr Hematol Oncol,2006

2. Treatment-related death in childhood acute lymphoblastic leukaemia in the Nordic countries: 1992-2001.;Christensen;Br J Haematol,2005

3. Infection-related complications during treatment for childhood acute lymphoblastic leukemia.;Inaba;Ann Oncol,2017

4. Association of bacteremic sepsis with long-term neurocognitive dysfunction in pediatric patients with acute lymphoblastic leukemia.;Cheung;JAMA Pediatr,2018

5. Bloodstream infections exacerbate incidence and severity of symptomatic glucocorticoid-induced osteonecrosis.;Finch;Pediatr Blood Cancer,2019

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