Patient-Level DNA Damage and Repair Pathway Profiles and Prognosis After Prostatectomy for High-Risk Prostate Cancer

Author:

Evans Joseph R.1,Zhao Shuang G.2,Chang S. Laura1,Tomlins Scott A.3,Erho Nicholas4,Sboner Andrea5,Schiewer Matthew J.6,Spratt Daniel E.1,Kothari Vishal1,Klein Eric A.7,Den Robert B.8,Dicker Adam P.8,Karnes R. Jeffrey9,Yu Xiaochun10,Nguyen Paul L.11,Rubin Mark A.5,de Bono Johann12,Knudsen Karen E.6,Davicioni Elai4,Feng Felix Y.13

Affiliation:

1. Department of Radiation Oncology, University of Michigan, Ann Arbor

2. Department of Radiation Oncology, University of Michigan, Ann Arbor2Beaumont Hospital - Dearborn, Transitional Year Program, Dearborn, Michigan

3. Department of Pathology, University of Michigan, Ann Arbor

4. GenomeDx Biosciences Inc, Vancouver, British Columbia, Canada

5. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York Presbyterian Hospitals, New York, New York

6. Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania

7. Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio

8. Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania

9. Department of Urology, Mayo Clinic, Rochester, Minnesota

10. City of Hope, Duarte, California

11. Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts

12. Drug Development Unit and Prostate Cancer Targeted Therapy Group, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, England

13. Department of Radiation Oncology, University of Michigan, Ann Arbor13Michigan Center for Translational Pathology, University of Michigan, Ann Arbor14Comprehensive Cancer Center, University of Michigan, Ann Arbor

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

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