Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers

Author:

Wallis Christopher J. D.1,Butaney Mohit2,Satkunasivam Raj3,Freedland Stephen J.45,Patel Sandip P.6,Hamid Omid7,Pal Sumanta K.8,Klaassen Zachary910

Affiliation:

1. Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada

2. School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland

3. Center for Outcomes Research, Department of Urology, Houston Methodist Hospital, Houston, Texas

4. Division of Urology, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California

5. Urology Section, Durham VA Medical Center, Durham, North Carolina

6. Moores Cancer Center-La Jolla, Department of Medicine, University of California, San Diego, La Jolla

7. Translational Research & Immunooncology, The Angeles Clinic & Research Institute, Los Angeles, California

8. Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, California

9. Division of Urology, Department of Surgery, Medical College of Georgia at Augusta University, Augusta

10. Georgia Cancer Center, Augusta University, Augusta, Georgia

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference42 articles.

1. Sex differences in immune responses.;Klein;Nat Rev Immunol,2016

2. A gender gap in autoimmunity.;Whitacre;Science,1999

3. SeXX matters in infectious disease pathogenesis.;vom Steeg;PLoS Pathog,2016

4. The Xs and Y of immune responses to viral vaccines.;Klein;Lancet Infect Dis,2010

5. Sex disparities in cancer incidence by period and age.;Cook;Cancer Epidemiol Biomarkers Prev,2009

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