Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures

Author:

,O’Toole Robert V.1,Joshi Manjari2,Carlini Anthony R.3,Murray Clinton K.4,Allen Lauren E.3,Huang Yanjie3,Scharfstein Daniel O.3,O’Hara Nathan N.1,Gary Joshua L.5,Bosse Michael J.6,Castillo Renan C.3,Bishop Julius A.7,Weaver Michael J.8,Firoozabadi Reza9,Hsu Joseph R.6,Karunakar Madhav A.6,Seymour Rachel B.6,Sims Stephen H.6,Churchill Christine6,Brennan Michael L.10,Gonzales Gabriela10,Reilly Rachel M.11,Zura Robert D.11,Howes Cameron R.11,Mir Hassan R.12,Wagstrom Emily A.13,Westberg Jerald13,Gaski Greg E.14,Kempton Laurence B.14,Natoli Roman M.14,Sorkin Anthony T.14,Virkus Walter W.14,Hill Lauren C.14,Hymes Robert A.15,Holzman Michael15,Malekzadeh A. Stephen15,Schulman Jeff E.15,Ramsey Lolita15,Cuff Jaslynn A. N.15,Haaser Sharon15,Osgood Greg M.16,Shafiq Babar16,Laljani Vaishali16,Lee Olivia C.17,Krause Peter C.17,Rowe Cara J.17,Hilliard Colette L.17,Morandi Massimo Max18,Mullins Angela18,Achor Timothy S.5,Choo Andrew M.5,Munz John W.5,Boutte Sterling J.5,Vallier Heather A.19,Breslin Mary A.19,Frisch H. Michael20,Kaufman Adam M.20,Large Thomas M.20,LeCroy C. Michael20,Riggsbee Christina21,Smith Christopher S.22,Crickard Colin V.22,Phieffer Laura S.23,Sheridan Elizabeth23,Jones Clifford B.24,Sietsema Debra L.24,Reid J. Spence25,Ringenbach Kathy25,Hayda Roman26,Evans Andrew R.26,Crisco M.J.26,Rivera Jessica C.27,Osborn Patrick M.27,Kimmel Joseph27,Stawicki Stanislaw P.28,Nwachuku Chinenye O.29,Wojda Thomas R.30,Rehman Saqib31,Donnelly Joanne M.31,Caroom Cyrus32,Jenkins Mark D.32,Boulton Christina L.1,Costales Timothy G.1,LeBrun Christopher T.1,Manson Theodore T.1,Mascarenhas Daniel C.1,Nascone Jason W.1,Pollak Andrew N.1,Sciadini Marcus F.1,Slobogean Gerard P.1,Berger Peter Z.1,Connelly Daniel W.1,Degani Yasmin1,Howe Andrea L.1,Marinos Dimitrius P.1,Montalvo Ryan N.1,Reahl G. Bradley1,Schoonover Carrie D.1,Schroder Lisa K.33,Vang Sandy33,Bergin Patrick F.34,Graves Matt L.34,Russell George V.34,Spitler Clay A.34,Hydrick Josie M.34,Teague David35,Ertl William35,Hickerson Lindsay E.35,Moloney Gele B.36,Weinlein John C.37,Zelle Boris A.38,Agarwal Animesh38,Karia Ravi A.38,Sathy Ashoke K.39,Au Brigham39,Maroto Medardo39,Sanders Drew39,Higgins Thomas F.40,Haller Justin M.40,Rothberg David L.40,Weiss David B.41,Yarboro Seth R.41,McVey Eric D.41,Lester-Ballard Veronica41,Goodspeed David42,Lang Gerald J.42,Whiting Paul S.42,Siy Alexander B.42,Obremskey William T.43,Jahangir A. Alex43,Attum Basem43,Burgos Eduardo J.43,Molina Cesar S.43,Rodriguez-Buitrago Andres43,Gajari Vamshi43,Trochez Karen M.43,Halvorson Jason J.44,Miller Anna N.44,Goodman James Brett44,Holden Martha B.44,McAndrew Christopher M.45,Gardner Michael J.45,Ricci William M.45,Spraggs-Hughes Amanda45,Collins Susan C.3,Taylor Tara J.3,Zadnik Mary3

Affiliation:

1. Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore

2. Department of Infectious Diseases, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore

3. Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

4. Department of Medicine, San Antonio Military Medical Center, San Antonio, Texas

5. Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston

6. Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina

7. Department of Orthopaedic Surgery, Stanford University, Palo Alto, California

8. Department of Orthopaedic Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts

9. Department of Orthopaedics and Sports Medicine, Harborview Medical Center/University of Washington, Seattle

10. Department of Orthopaedic Surgery, Baylor Scott and White Memorial Center, Temple, Texas

11. Department of Orthopaedic Surgery, Duke University, Durham, North Carolina

12. Florida Orthopaedic Institute/Tampa General Hospital, Tampa

13. Department of Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, Minnesota

14. Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis

15. Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia

16. Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland

17. Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans

18. Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, Shreveport

19. Department of Orthopaedics, MetroHealth, Cleveland, Ohio

20. Orthopaedic Trauma Service, Mission Health, Asheville, North Carolina

21. Research Institute, Mission Health, Asheville, North Carolina

22. Department of Orthopaedic Surgery, Naval Medical Center Portsmouth, Portsmouth, Virginia

23. Department of Orthopaedics, Ohio State University, Wexner Medical Center, Columbus

24. Spectrum Health, Grand Rapids, Michigan

25. Department of Orthopaedics and Rehabilitation, Penn State Health, Hershey, Pennsylvania

26. Department of Orthopedic Surgery, Brown University/Rhode Island Hospital, Providence

27. Department of Orthopaedic Surgery, San Antonio Military Medical Center, San Antonio, Texas

28. Department of Research and Innovation, St. Luke’s University Health Network, Bethlehem, Pennsylvania

29. Department of Orthopedic Surgery, St. Luke’s University Health Network, Bethlehem, Pennsylvania

30. Department of Family Medicine, St. Luke’s University Health Network, Bethlehem, Pennsylvania

31. Department of Orthopaedic Surgery and Sports Medicine, Temple University, Philadelphia, Pennsylvania

32. Department of Orthopaedics, Texas Tech University Health Sciences Center, Lubbock

33. Department of Orthopaedic Surgery, University of Minnesota–Regions Hospital, St Paul

34. Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson

35. Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City

36. Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

37. Department of Orthopaedic Surgery, University of Tennessee–Campbell Clinic, Memphis

38. Department of Orthopaedics, University of Texas Health at San Antonio, San Antonio

39. Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas

40. Department of Orthopaedics, University of Utah, Salt Lake City

41. Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville

42. Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison

43. Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee

44. Department of Orthopaedic Surgery and Rehabilitation, Wake Forest Baptist University Medical Center, Winston-Salem, North Carolina

45. Department of Orthopedic Surgery, Washington University in St Louis/Barnes Jewish Hospital, St Louis, Missouri

Publisher

American Medical Association (AMA)

Subject

Surgery

Reference28 articles.

1. Complications following limb-threatening lower extremity trauma.;Harris;J Orthop Trauma,2009

2. Noncontiguous and open fractures of the lower extremity: epidemiology, complications, and unplanned procedures.;Chen;Injury,2016

3. Infection after fracture fixation: Current surgical and microbiological concepts.;Metsemakers;Injury,2018

4. Guidelines for the prevention of infection after combat-related injuries.;Hospenthal;J Trauma,2008

5. Guidelines for the prevention of infections associated with combat-related injuries: 2011 update: endorsed by the Infectious Diseases Society of America and the Surgical Infection Society.;Hospenthal;J Trauma,2011

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