Worldwide Prevalence and Disability From Mental Disorders Across Childhood and Adolescence-Reference-Cited by-同舟云学术

Worldwide Prevalence and Disability From Mental Disorders Across Childhood and Adolescence

Published:2024-01-31 Issue: Volume: Page:
ISSN:2168-622X
Container-title:JAMA Psychiatry
language:en
Short-container-title:JAMA Psychiatry

Author:

Kieling Christian¹²³,Buchweitz Claudia²,Caye Arthur²⁴,Silvani Juliana⁵,Ameis Stephanie H.⁶⁷,Brunoni André R.⁸,Cost Katherine T.⁹¹⁰,Courtney Darren B.¹¹,Georgiades Katholiki¹²,Merikangas Kathleen Ries¹³,Henderson Joanna L.¹¹¹⁴,Polanczyk Guilherme V.⁸,Rohde Luis Augusto¹²³⁴,Salum Giovanni A.¹²¹⁵,Szatmari Peter¹⁶

Affiliation:

1. Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

2. Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

3. Child and Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

4. National Center for Research and Innovation in Mental Health (CISM), São Paulo, Brazil

5. Graduate Program in Epidemiology, Department of Social Medicine, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

6. Campbell Family Mental Health Research Institute, Cundill Centre for Child and Youth Depression, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

7. Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

8. Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo, Universidade de São Paulo, São Paulo, Brazil

9. Department of Psychiatry and Behavioural Neurosciences, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada

10. Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada

11. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

12. Department of Psychiatry and Behavioural Neurosciences & Offord Centre for Child Studies, McMaster University, Hamilton, Ontario, Canada

13. Section on Developmental Genetic Epidemiology, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland

14. Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

15. Child Mind Institute, New York, New York

16. Cundill Centre for Child and Youth Depression, Division of Child and Youth Mental Health, Centre for Addiction and Mental Health & University of Toronto, University of Toronto, Toronto, Ontario, Canada

Abstract

ImportanceThe period from childhood to early adulthood involves increased susceptibility to the onset of mental disorders, with implications for policy making that may be better appreciated by disaggregated analyses of narrow age groups.ObjectiveTo estimate the global prevalence and years lived with disability (YLDs) associated with mental disorders and substance use disorders (SUDs) across 4 age groups using data from the 2019 Global Burden of Disease (GBD) study.Design, Setting, and ParticipantsData from the 2019 GBD study were used for analysis of mental disorders and SUDs. Results were stratified by age group (age 5 to 9, 10 to 14, 15 to 19, and 20 to 24 years) and sex. Data for the 2019 GBD study were collected up to 2018, and data were analyzed for this article from April 2022 to September 2023.ExposureAge 5 to 9 years, 10 to 14 years, 15 to 19 years, and 20 to 24 years.Main Outcomes and MeasuresPrevalence rates with 95% uncertainty intervals (95% UIs) and number of YLDs.ResultsGlobally in 2019, 293 million of 2516 million individuals aged 5 to 24 years had at least 1 mental disorder, and 31 million had an SUD. The mean prevalence was 11.63% for mental disorders and 1.22% for SUDs. For the narrower age groups, the prevalence of mental disorders was 6.80% (95% UI, 5.58-8.03) for those aged 5 to 9 years, 12.40% (95% UI, 10.62-14.59) for those aged 10 to 14 years, 13.96% (95% UI, 12.36-15.78) for those aged 15 to 19 years, and 13.63% (95% UI, 11.90-15.53) for those aged 20 to 24 years. The prevalence of each individual disorder also varied by age groups; sex-specific patterns varied to some extent by age. Mental disorders accounted for 31.14 million of 153.59 million YLDs (20.27% of YLDs from all causes). SUDs accounted for 4.30 million YLDs (2.80% of YLDs from all causes). Over the entire life course, 24.85% of all YLDs attributable to mental disorders were recorded before age 25 years.Conclusions and RelevanceAn analytical framework that relies on stratified age groups should be adopted for examination of mental disorders and SUDs from childhood to early adulthood. Given the implications of the early onset and lifetime burden of mental disorders and SUDs, age-disaggregated data are essential for the understanding of vulnerability and effective prevention and intervention initiatives.

Publisher

American Medical Association (AMA)

Subject

Psychiatry and Mental health

Link

https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2814639/jamapsychiatry_kieling_2024_oi_230100_1706545322.71733.pdf

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