Placenta peptides: antibacterial effects-Reference-Cited by-同舟云学术

Placenta peptides: antibacterial effects

Published:2024-01-22 Issue:4 Volume: Page:15-22
ISSN:2686-8830
Container-title:Pharmacokinetics and Pharmacodynamics
language:
Short-container-title:Fk&Fd

Author:

Torshin I. Yu.¹^ORCID,Bogacheva T. E.²^ORCID,Gromova O. A.¹^ORCID

Affiliation:

1. FRC "Computer Science and Control" RAS

2. FSBEI HE "Ivanovo State Medical Academy" MOH Russia

Abstract

Mass spectrometric sequencing of peptides in Laennec indicated the presence of 5 peptides in the drug, the biological activity of which may determine the antibacterial properties of the drug. The most significant result of this study is the presence in Laennec of a fragment of the antibacterial peptide cathelicidin (LL-37), an important vitamin D-dependent factor of innate immunity. Other Laennec peptides help reduce excess inflammation by inhibiting the activity of the NF-kB protein, which mediates the effects of TNF-α.

Publisher

Publishing House OKI

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

Reference38 articles.

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