Affiliation:
1. Main Military Clinical Hospital named after academician N. N. Burdenko of the Ministry of Defense of the Russian Federation; Moscow State University of Food Production — Medical Institute of Continuous Education
2. 301st Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Abstract
The problem of antimicrobial therapy (AMT) for the new coronavirus infection has been the cornerstone of practical healthcare since its emergence to the present day. The article summarizes a number of problems concerning the unjustified prescription of AMT based on the data of foreign and domestic studies, as well as actual clinical practice. On the one hand, viral damage to the lung tissue during COVID-19 is difficult to distinguish from community-acquired or secondary bacterial pneumonia; it prompts clinicians to prevent possible bacterial complications in the lungs by prescribing broad-spectrum antibiotics starting from the first day. On the other hand, the presence of clear clinical and biological markers of bacterial pneumonia; and COVID-19 makes it possible not to use antibiotics in routine practice, at least in the early stages of treatment. The introduction of procalcitonin as a biomarker of bacterial infection in COVID-19 into everyday clinical practice has a reasonable, methodical, and scientific approach to prescribing antibiotics.
Subject
Infectious Diseases,Microbiology (medical),General Medicine,Microbiology
Reference29 articles.
1. Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Vremennye metodicheskie rekomendatsii. Profilaktika, diagnostika i lechenie novoi koronavirusnoi infektsii (COVID-19). Versiya 15 (22.02.2022). Dostupno po: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/059/392/original/VMR_COVID-19_V15.pdf. Ssylka aktivna na 10.07.2022. [Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Vremennye metodicheskie rekomendatsii. Profilaktika, diagnostika i lechenie novoi koronavirusnoi infektsii (COVID-19). Versiya 15 (22.02.2022). Available from: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/059/392/original/VMR_COVID-19_V15.pdf. Accessed: July 10, 2022. (in Russian)]
2. Zaitsev A.A., Chernov S.A., Kryukov E.V., Golukhova E.Z., Rybka M.M. Prakticheskii opyt vedeniya patsientov s novoi koronavirusnoi infektsiei COVID-19 v statsionare (predvaritel'nye itogi i rekomendatsii). Lechashchii vrach. 2020; 6: 74–79. [Zaytsev A.A., Chernov S.A., Kryukov E.V., Golukhova E.S., Rybka M.M. Practical experience of managing patients with novel coronavirus infection COVID-19 in hospital (preliminary results and guidelines). Lechashchiy Vrach Journal. 2020; 6: 74–79 (in Russian)]
3. Zaitsev, A. A. Pis'mo v redaktsiyu. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya. 2020; 22 (2): 84–86. https://doi.org/10.36488/cmac.2020.2.84-86. [Zaytsev A.A. Letter to editors. Clinical Microbiology and Antimicrobial Chemotherapy. 2020; 22 (2): 84–86 (in Russian)]
4. Zaitsev A.A., Chernov S.A., Stets V.V. i dr. Algoritmy vedeniya patsientov s novoi koronavirusnoi infektsiei COVID-19 v statsionare. Metodicheskie rekomendatsii. Consilium Medicum. 2020; 22 (11): https://doi.org/10.26442/20751753.2020.11.200520. [Zaitsev A.A., Chernov S.A., Stets V.V. et al. Algorithms for the management of patients with a new coronavirus COVID-19 infection in a hospital. Guidelines. Consilium Medicum. 2020; 22 (11): https://doi.org/10.26442/20751753.2020.11.200520. (in Russian)]
5. Griffin D.O., Brennan-Rieder D., Ngo B. et. al. The Importance of Understanding the Stages of COVID-19 in Treatment and Trials. AIDS Rev. 2021 Feb 8; 23 (1): 40–47. doi: 10.24875/AIDSRev.200001261.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献