Extraocular Muscle Reveals Selective Vulnerability of Type IIB Fibers to Respiratory Chain Defects Induced by Mitochondrial DNA Alterations

Author:

Oexner Rafael R.1,Pla-Martín David12,Paß Thomas1,Wiesen Martin H. J.3,Zentis Peter2,Schauss Astrid2,Baris Olivier R.14,Kimoloi Sammy15,Wiesner Rudolf J.126

Affiliation:

1. Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, University of Köln, Köln, Germany

2. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Köln, Köln, Germany

3. Center of Pharmacology, Therapeutic Drug Monitoring Unit, Medical Faculty, University Hospital of Köln, Köln, Germany

4. Equipe MitoLab, UMR CNRS 6015, INSERM U1083, Institut MitoVasc, Université d'Angers, Angers, France

5. Department of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, Kakamega, Kenya

6. Center for Molecular Medicine Cologne, University of Köln, Köln, Germany

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

General Medicine

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