1. From the Institute of Zoology, Department of Cell and Matrix Biology, Johannes Gutenberg-University of Mainz, Mainz, Germany; and
2. the Department of Genetics and The Rappaport Family Institute for Research in the Medical Sciences, Rappaport Faculty of Medicine, and
3. the Edith and Joseph Fischer Enzyme Inhibitors Laboratory, Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel.