ATG8ylation of proteins: A way to cope with cell stress?-Reference-Cited by-同舟云学术

ATG8ylation of proteins: A way to cope with cell stress?

Published:2021-10-20 Issue:11 Volume:220 Page:
ISSN:0021-9525
Container-title:Journal of Cell Biology
language:en
Short-container-title:

Author:

Carosi Julian M.¹^ORCID,Nguyen Thanh N.²^ORCID,Lazarou Michael²^ORCID,Kumar Sharad³^ORCID,Sargeant Timothy J.¹^ORCID

Affiliation:

1. Lysosomal Health in Ageing, Hopwood Centre for Neurobiology, South Australian Health & Medical Research Institute, Adelaide, South Australia, Australia

2. Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia

3. Centre for Cancer Biology, University of South Australia, Adelaide, South Australia, Australia

Abstract

The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.

Funder

Lysosomal Health in Ageing

South Australian Health and Medical Research Institute

Australian National Health and Medical Research Council

Australian Research Council

ARC

Publisher

Rockefeller University Press

Subject

Cell Biology

Link

http://rupress.org/jcb/article-pdf/doi/10.1083/jcb.202108120/1424386/jcb_202108120.pdf