Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras-Reference-Cited by-同舟云学术

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Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

Published:1998-04-01 Issue:4 Volume:13 Page:581-589
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Luckman Steven P.,Hughes David E.,Coxon Fraser P.,Russell R. Graham G.,Rogers Michael J.

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Reference48 articles.

1. Bisphosphonates: Pharmacology and use in the treatment of tumour-induced hypercalcaemia and metastatic bone disease;Fleisch;Drugs,1991

2. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis;Liberman;N Engl J Med,1995

3. The management of Paget's disease of bone;Delmas;N Engl J Med,1997

4. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-β,γ-dichloromethylene) triphosphate, by mammalian cells in vitro;Frith;J Bone Miner Res,1997

5. Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo;Hughes;J Bone Miner Res,1995

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