1. Ministry of Education Key Laboratory of diagnostic Medicine, School of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China
2. department of Biostatistics, School of Public Health and Management, Chongqing Medical University, Chongqing 400016, P.R. China
3. Key Laboratory of Molecular Biology for Infectious diseases of The Ministry of Education of china, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400037, P.R. China
4. Molecular Oncology Laboratory, department of Orthopedic Surgery and Rehabilitation Medicine, The University of Chicago Medical center, Chicago, IL 60637, USA