P40 and TTF‑1 double‑expressing non‑small cell lung cancer with EML4‑ALK and PIK3CA gene mutations: A case report and review of the literature

Author:

Cai Ying1,Liu Hongsheng2,Chen Xiaodan2,Yang Junjie2,Huang Bin2

Affiliation:

1. Department of Respiratory Medicine, The First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang 311200, P.R. China

2. Department of Pathology, The First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang 311200, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference18 articles.

1. Challenging lung carcinoma with coexistent ΔNp63/p40 and thyroid transcription factor-1 labeling within the same individual tumor cells;Pelosi;J Thorac Oncol,2015

2. Non-small cell lung carcinoma with diffuse coexpression of thyroid transcription factor-1 and ΔNp63/p40;Hayashi;Hum Pathol,2018

3. When tumor doesn't read textbook. Third case of TTF1 and p40 co-expression in the same tumour cells in a non-small cell carcinoma;Spinelli;A potential new entity to consider? Pathologica,2019

4. Coexpression of ΔNp63/p40 and TTF1 within most of the same individual cells identifies life threatening NSCLC featuring squamous and glandular biphenotypic differentiation: Clinicopathologic correlations;Pelosi;JTO Clin Res Rep,2021

5. Coexpression of thyroid transcription factor 1 and P40 in non-small cell lung cancer cells: A case report;Chen;Chin J Pathol,2022

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