ORMDL3‑mediated bronchial epithelial pyroptosis leads to lung inflammation in obese mice with asthma

Author:

Liu Fan1,Sun Yan2,Zhou Yun3,Gao Yuye2,Song Qijun2,Yang Jianmei2,Xu Chao4,Li Guimei2

Affiliation:

1. Children's Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100020, P.R. China

2. Department of Pediatrics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China

3. Department of Pediatrics, Shandong Provincial Lanling People's Hospital, Linyi, Shandong 277799, P.R. China

4. Department of Endocrinology and Metabolism, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Reference66 articles.

1. Obesity and asthma;Peters;J Allergy Clin Immunol,2018

2. Current asthma prevalence by weight status among adults: United States, 2001-2014;Akinbami;NCHS Data Brief,2016

3. Asthma and obesity: Two diseases on the rise and bridged by inflammation;Bantulà;J Clin Med,2021

4. β-caryophyllene ameliorated obesity-associated airway hyperresponsiveness through some non-conventional targets;Pathak;Phytomedicine,2021

5. Impact of obesity and ovariectomy on respiratory function in female mice;Lopes;Respir Physiol Neurobiol,2021

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