PEDF inhibits non‑small cell lung cancer proliferation by suppressing autophagy through downregulation of AMPK‑ULK1 signaling

Author:

Miao Haoran1,Hui Hongliang1,Li Huaming1,Lin Yangui1,Li Dan2,Luo Min1,Jiang Bo1,Zhang Yiqian1

Affiliation:

1. Department of Thoracic Cardiovascular Surgery, The Eighth Affiliated Hospital of Sun Yat‑sen University, Shenzhen, Guangdong 518000, P.R. China

2. Community Health Center, The Eighth Affiliated Hospital of Sun Yat‑sen University, Shenzhen, Guangdong 518000, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,General Medicine

Reference48 articles.

1. ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis;Chung;Autophagy,2017

2. Lung cancer identification: A review on detection and classification;Thakur;Cancer Metastasis Rev,2020

3. Classification and pathology of lung cancer;Zheng;Surg Oncol Clin N Am,2016

4. Molecular diagnostics and targeted therapies in non-small cell lung cancer (NSCLC): An update;Jonna;Discov Med,2019

5. Autophagy and mitophagy in cancer metabolic remodelling;Ferro;Semin Cell Dev Biol,2020

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