Licochalcone H Targets EGFR and AKT to Suppress the Growth of Oxaliplatin -Sensitive and -Resistant Colorectal Cancer Cells

Author:

Lee Seung-On1,Lee Mee-Hyun2,Kwak Ah-Won3,Lee Jin-Young4,Yoon Goo5,Joo Sang Hoon6,Choi Yung Hyun7,Park Jin Woo15,Shim Jung-Hyun158

Affiliation:

1. Department of Biomedicine, Health & Life Convergence Sciences, BK21 Four, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea

2. College of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea

3. Biosystem Research Group, Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea

4. Department of Biological Sciences, Keimyung University, Daegu 42601, Republic of Korea

5. Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea

6. College of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Republic of Korea

7. Department of Biochemistry, College of Korean Medicine, Dong-Eui University, Busan 47227, Republic of Korea

8. The China-US (Henan) Hormel Cancer Institute, Zhengzhou 450008, China

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

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