A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region
Author:
Affiliation:
1. Department of Environmental & Health Chemistry, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea
2. HaplnSicence Inc., Seongnam 13494, Republic of Korea
Funder
Chung-Ang University
Inha University
National Research Foundation of Korea
Ministry of Science and ICT, South Korea
Publisher
The Korean Society of Applied Pharmacology
Subject
Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry
Link
http://pdf.medrang.co.kr/BT2/2022/030/BT030-06-529.pdf
Reference50 articles.
1. T-cell regulation by CD28 and CTLA-4
2. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.
3. Quality of Life in Patients with Rheumatoid Arthritis
4. Site-specific monitoring of N-Glycosylation profiles of a CTLA4-Fc-fusion protein from the secretory pathway to the extracellular environment
5. Collagen-induced arthritis
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