A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone. Inhibition of Collagen Fibril Assembly-Reference-Cited by-同舟云学术

A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone. Inhibition of Collagen Fibril Assembly

Published:2017-07 Issue:1 Volume:57 Page:77-90
ISSN:1044-1549
Container-title:American Journal of Respiratory Cell and Molecular Biology
language:en
Short-container-title:Am J Respir Cell Mol Biol

Author:

Knüppel Larissa¹,Ishikawa Yoshihiro²³,Aichler Michaela⁴,Heinzelmann Katharina¹,Hatz Rudolf⁵⁶,Behr Jürgen⁷⁶,Walch Axel⁴,Bächinger Hans Peter²³,Eickelberg Oliver¹⁸,Staab-Weijnitz Claudia A.¹^ORCID

Affiliation:

1. Comprehensive Pneumology Center, and

2. Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon

3. Research Department, Shriners Hospital for Children, Portland, Oregon

4. Research Unit Analytical Pathology, Helmholtz-Zentrum München, Munich, Germany

5. Thoraxchirurgisches Zentrum, Klinik für Allgemeine-, Viszeral-, Transplantations-, Gefäß- und Thoraxchirurgie, Klinikum Großhadern, and

6. Asklepios Fachkliniken München-Gauting, Munich, Germany; and

7. Medizinische Klinik und Poliklinik V, Klinikum der Ludwig-Maximilians-Universität, Ludwig-Maximilians-Universität, Munich, Germany

8. Pulmonary and Critical Care Medicine University, Colorado Anschutz Medical Campus, Denver, Colorado

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Link

http://www.atsjournals.org/doi/pdf/10.1165/rcmb.2016-0217OC

Reference46 articles.

1. Classification and Natural History of the Idiopathic Interstitial Pneumonias

2. The pathogenesis of idiopathic pulmonary fibrosis

3. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

4. The Impact of TGF-β on Lung Fibrosis

5. Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

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