Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction-Reference-Cited by-同舟云学术

Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction

Published:2024-06-26 Issue:1 Volume:2 Page:20240028
ISSN:
Container-title:Aging Biology
language:en
Short-container-title:AgingBio

Author:

Shmookler Reis Robert J.¹²³⁴,Ayyadevara Srinivas¹²³⁴,Ganne Akshatha¹,Mainali Nirjal¹²,Balasubramaniam Meenakshisundaram¹³,Atluri Ramani¹³,Pahal Sonu¹²,Asante Joseph J.¹²,Nagel Corey⁵,Vallurupalli Srikanth³⁶

Affiliation:

1. Department of Geriatrics and Institute on Aging, University of Arkansas for Medical Sciences

2. Bioinformatics Program, University of Arkansas at Little Rock and University of Arkansas for Medical Sciences

3. Central Arkansas Veterans Healthcare System

4. Geriatric Research Education and Clinical Center (GRECC), Veterans Healthcare Administration

5. College of Nursing, University of Arkansas for Medical Sciences

6. Department of Internal Medicine, Division of Cardiology, University of Arkansas for Medical Sciences

Publisher

Aging Biology LLC

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3. Associations between potentially modifiable risk factors and Alzheimer disease: A Mendelian randomization study;Ostergaard;PLoS Med.,2015

4. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer’s hippocampus from normal controls;Ayyadevara;Aging Cell,2016

5. Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain;Mainali;Mol. Cell Biochem.,2023