Extraction, purification, characterization and antidiabetic mechanisms of plant polysaccharides: a critical review-Reference-Cited by-同舟云学术

Extraction, purification, characterization and antidiabetic mechanisms of plant polysaccharides: a critical review

Published:2024-08-29 Issue: Volume: Page:
ISSN:1303-829X
Container-title:Turkish Journal of Biochemistry
language:en
Short-container-title:

Author:

Li Meng¹²^ORCID,Law Douglas³^ORCID,Zhu Song⁴⁵^ORCID,Najm Ahmed Abdul kareem⁴^ORCID,Fazry Shazrul⁴⁶^ORCID,Othman Babul Airianah⁴⁶^ORCID

Affiliation:

1. Department of Biological Sciences and Biotechnology, Faculty of Science and Technology , 61775 Universiti Kebangsaan Malaysia , Bangi , Selangor , Malaysia

2. College of Horticulture , Xinyang Agriculture and Forestry University , Xinyang , Henan , China

3. Faculty of Health and Life Sciences , INTI International University , Nilai , Malaysia

4. Department of Food Sciences, Faculty of Science and Technology , Universiti Kebangsaan Malaysia , Bangi , Selangor , Malaysia

5. Department of Health Management , Heze Medical College , Heze , Shandon , China

6. Innovation Center for Confectionary Technology (MANIS), Faculty of Science and Technology , Universiti Kebangsaan Malaysia , Bangi , Selangor , Malaysia

Abstract

Abstract Diabetes mellitus (DM) represents a heterogeneous and multifactorial metabolic disorder, leading to diverse economic challenges and health complications, significantly affecting individuals’ lives. Type 2 diabetes (T2DM) stands as the predominant form of diabetes, with its onset influenced by a range of genetic and environmental factors. Currently, conventional diabetic medications are employed in clinical practice, but they may entail certain side effects. Fortunately, diverse natural polysaccharides extracted from plants exhibit antidiabetic properties, which have been demonstrated to effectively mitigate hyperglycemia, reverse insulin resistance, and forestall complications associated with diabetes. Consequently, exploring the utilization of these polysaccharides as adjuncts to conventional therapies has emerged as a novel research direction in recent years. Thus, this review centers on the extraction, purification, and characterization of plant polysaccharides, providing an overview of the advancements in the antidiabetic effects and mechanisms of natural polysaccharides. This perspective offers fresh insights to explore potential research domains and enhances understanding for the development of diabetic drugs derived from polysaccharides.

Funder

Fundamental Research Grant Scheme, Faculty of Science and Technology, Universiti Kebangsaan Malaysia

Academic New Talent Training Program, Xinyang Agriculture and Forestry University

INTI International University Seed grant

Evaluation of characteristic germplasm resources and selection of good germplasm of wild oil tea in Dabie Mountain, Henan Province, China

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/tjb-2024-0071/pdf

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