Synthesis of greener silver nanoparticle-based chitosan nanocomposites and their potential antimicrobial activity against oral pathogens

Abstract

Abstract In the present investigation, silver nanoparticles (AgNPs) and silver nanoparticle-based chitosan nanocomposite were synthesized using Cissus arnottiana leaf extract. The biosynthesized nanoparticles and nanocomposites were characterized using SEM, TEM, and AFM to uncover the morphological characteristics such as size and shape. The SEM image depicts the size of the nanocomposite to be 30–40 nm and shape as spherical. The TEM results reveal the shape of the nanocomposite to be spherical and size around 10–60 nm. The XRD results show the crystalline nature of the AgNPs-based chitosan nanocomposite. The SAED analysis pattern seems to be concordant with the XRD results. The AFM image ensured the precise surface morphology of the synthesized silver nanocomposite in the 3-dimensional pattern. The antimicrobial efficacy of the biosynthesized AgNPs, AgNP nanocomposite, and chitosan nanoparticles was tested against oral pathogens. The results revealed a potential antimicrobial effect, which states that it must be converted into nanomedicine to meet future biomedical needs.