Affiliation:
1. Department of Gynecology and Obstetrics , University Hospital of Münster , Münster , Germany
2. Institute of Biostatistics and Clinical Research, University of Münster , Münster , Germany
Abstract
Abstract
Objectives
The aim of this study was to assess the value of cervical strain elastography and Cervical Sliding Sign (CSS) for predicting spontaneous preterm birth (sPTB).
Methods
In our case-control study we performed an elastographic assessment of the cervix in 82 cases of preterm birth (preterm group) and 451 control pregnancies (control group) between the 20th and 37th week of gestation. We divided the anterior cervical lip first into two (“Intern2”, “Extern2”) and into three sectors (“Intern3”, “Middle3”, “Extern3”). The tissue deformation pattern after local compression with an ultrasound probe was recorded. We distinguished between an irregularly distributed (“Spotting”) and homogeneous pattern presentation. Additionally, the presence of a sliding of the anterior against the posterior cervical lip (positive CSS) during compression was evaluated. A logistic regression analysis and the Akaike Information Criterion (AIC) were used to estimate the probability of sPTB and to select a prediction model.
Results
Spotting and positive CSS occurred more frequently in the preterm group compared to control group (97.8 vs. 2.2%, p<0.001; 26.8 vs. 4.2%, p<0.001; respectively). The model with the parameters week of gestation at ultrasound examination, Intern3, Middle3 and CSS was calculated as the highest quality model for predicting sPTB. The AUC (Area Under the Curve) was higher for this parameter combination compared to cervical length (CL) (0.926 vs. 0.729).
Conclusions
Cervical strain elastography pattern analysis may be useful for the prediction of sPTB, as the combination of Spotting analysis and CSS is superior to CL measurement alone.
Subject
Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献