Pyroptosis-related noncoding RNAs and cancer involvement-Reference-Cited by-同舟云学术

Pyroptosis-related noncoding RNAs and cancer involvement

Published:2023-06-15 Issue:0 Volume:0 Page:
ISSN:1765-2839
Container-title:Oncologie
language:en
Short-container-title:

Author:

Chai Binshu¹,Qiu Jianhua²,Pan Wei¹,Ma Zhongliang¹^ORCID

Affiliation:

1. Lab for Noncoding RNA & Cancer, School of Life Sciences , Shanghai University , Shanghai , China

2. Department of Anesthesiology , Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , China

Abstract

Abstract Cell pyroptosis, an inflammatory and programmed cell necrosis, is also an important cause of multiple organ damage and immunosuppression. Pyroptosis, a new kind of programmed cell death, leads to cleavage of the pyroptotic protein Gasdermin family and ultimately to membrane pore formation, cell shrinkage, plasma membrane cleavage, chromatin disruption and release of pro-inflammatory components. Various studies found that pyroptosis had a key role in cancer and inflammatory diseases. Gasdermin family is key protein in pyrotopsis. Non-coding RNAs have a potential role in cell pyrotosis which regulate immunity and cell death. This article reviews cell pyroptosis, GSDM family and the regulatory role of non-coding RNAs.

Funder

Shanghai Science and Technology Committee

Publisher

Walter de Gruyter GmbH

Subject

Oncology

Link

https://www.degruyter.com/document/doi/10.1515/oncologie-2023-0045/pdf

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