Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis

Author:

Abdelwahed Mahmoud Tareq12,Hegazy Maha A.3,Mohamed Ekram H.12

Affiliation:

1. Pharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt (BUE) , Cairo , Egypt

2. The Center for Drug Research and Development (CDRD), Faculty of Pharmacy, The British University in Egypt , Cairo , Egypt

3. Analytical Chemistry Department, Faculty of Pharmacy, Cairo University , Kasr-El Aini Street , 11562 Cairo , Egypt

Abstract

Abstract Ashwagandha (Withania somnifera) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antioxidant, adaptogen, memory enhancer, and possess an effect on neurodegenerative diseases. Additionally, it was revealed that the plant exerts antibacterial, antiviral, antitumor, aphrodisiac, and cardiovascular protection activities. Due to the biological and nutritional importance of nutraceuticals, particularly ashwagandha, and as part of the ongoing research of the natural products and its bioactive phytochemicals, this review aims to summarize the recent analytical techniques that have been reported for the determination of different chemical constituents of Withania somnifera quantitatively and qualitatively, and to highlight new challenges.

Publisher

Walter de Gruyter GmbH

Subject

Analytical Chemistry

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