Fucosylation of serum glycoproteins in lung cancer patients

Author:

Kossowska Barbara,Ferens-Sieczkowska Mirosława,Gancarz Roman,Passowicz-Muszyńska Ewa,Jankowska Renata

Abstract

AbstractIncreased expression of sialyl Lewis X or A antigens on metastatic cancer cells leads to their selectin-mediated extravasation. Profound fucosylation of the serum microenvironment may be a factor that interrupts adhesion and influences the formation of metastases. In this study we quantitatively analyzed fucosylation of serum glycoproteins in small-cell and non-small-cell lung cancer patients. Fucosylation of four chosen glycoprotein bands was measured as the reactivity with

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry, medical,Clinical Biochemistry,General Medicine

Reference35 articles.

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