Author:
Perkins Katherine L.,Arranz Amaia M.,Yamaguchi Yu,Hrabetova Sabina
Abstract
AbstractMutant mice deficient in hyaluronan (HA) have an epileptic phenotype. HA is one of the major constituents of the brain extracellular matrix. HA has a remarkable hydration capacity, and a lack of HA causes reduced extracellular space (ECS) volume in the brain. Reducing ECS volume can initiate or exacerbate epileptiform activity in many
Cited by
44 articles.
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