Affiliation:
1. Laboratório de Síntese Orgânica Limpa – LASOL, CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, 96010-900 Pelotas , RS , Brazil
Abstract
Abstract
Carbon–carbon and carbon-heteroatom bond forming reactions are strategically employed for the generation of a variety of heterocyclic systems. This class of compounds represents the most general structural unit, present in many natural compounds. They are recognized for their valuable biologically properties and wide range of applications in medicinal, pharmaceutical, and other related fields of chemistry. This is an updated review on the use of dicarbonyl compounds under environmentally friendly conditions to access a series of heterocyclic structures, e.g., quinoxaline, quinazolinones, benzochalcogenazoles, indoles, among others. Synthetic protocols involving copper-catalyzed, multicomponent and cascade reactions, decarboxylative cyclization, recycling of CO2, and electrochemical approaches are presented and discussed.
Subject
General Physics and Astronomy,General Materials Science,General Chemistry
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