Tumor microenvironment in treatment of glioma

Author:

Li Guijie1,Qin Zhigang2,Chen Zhuo2,Xie Lijuan3,Wang Ren4,Zhao Hang2

Affiliation:

1. Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Union hospital of Jilin University, Changchun130033, China

2. Department of Neurosurgery, China-Japan Union hospital of Jilin University, Changchun130033,China

3. Department of Vascular Surgery, China-Japan Union hospital of Jilin University, Changchun130033, China

4. Department of Neurosurgery, The People’s Hospital of Fusong County of Jilin Province, Fusong134500, China

Abstract

AbstractGlioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in different processes of tumor. In this paper, we describe the effects of tumor microenvironment on glioma proliferation, invasion and treatments. By explaining underlying mechanisms and enumerating new therapy strategies employing tumor microenvironment, we aim to provide novel ideas to improve clinical outcomes of glioma.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

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