Super-rapid race for saving lives by developing COVID-19 vaccines

Author:

Uttarilli Anusha12,Amalakanti Sridhar1,Kommoju Phaneeswara-Rao1,Sharma Srihari1,Goyal Pankaj3,Manjunath Gowrang Kasaba1,Upadhayay Vineet1,Parveen Alisha4,Tandon Ravi5,Prasad Kumar Suranjit6,Dakal Tikam Chand7,Ben Shlomo Izhar8,Yousef Malik910ORCID,Neerathilingam Muniasamy12,Kumar Abhishek12ORCID

Affiliation:

1. Institute of Bioinformatics , International Technology Park , Bangalore 560066 , India

2. Manipal Academy of Higher Education (MAHE) , Manipal 576104 , Karnataka , India

3. Department of Biotechnology, School of Life Sciences , Central University of Rajasthan , Bandarsindri , Kishangarh 305817 , Rajasthan , India

4. Institute for Experimental Surgery, University of Rostock , Rostock D18057 , Germany

5. School of Biotechnology , Jawaharlal Nehru University , New Delhi 110067 , India

6. Centre of Environmental Science, Institute of Interdisciplinary Studies , University of Allahabad (A Central University) , Allahabad , Uttar Pradesh , India

7. Genome & Computational Biology Lab, Department of Biotechnology , Mohanlal Sukhadia University , Udaipur 313001 , Rajasthan , India

8. Program of Emergency Medicine , Zefat Academic College , Safed 13206 , Israel

9. Department of Information Systems , Zefat Academic College , Zefat 13206 , Israel

10. Galilee Digital Health Research Center (GDH) , Zefat Academic College , Zefat 13206 , Israel

Abstract

Abstract The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people and claimed thousands of lives. Starting in China, it is arguably the most precipitous global health calamity of modern times. The entire world has rocked back to fight against the disease and the COVID-19 vaccine is the prime weapon. Even though the conventional vaccine development pipeline usually takes more than a decade, the escalating daily death rates due to COVID-19 infections have resulted in the development of fast-track strategies to bring in the vaccine under a year’s time. Governments, companies, and universities have networked to pool resources and have come up with a number of vaccine candidates. Also, international consortia have emerged to address the distribution of successful candidates. Herein, we summarize these unprecedented developments in vaccine science and discuss the types of COVID-19 vaccines, their developmental strategies, and their roles as well as their limitations.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

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