Phytofunctionalized silver nanoparticles: green biomaterial for biomedical and environmental applications

Abstract

AbstractVariegated physicochemical routes with emerging modifications have been adopted and reported for silver nanoparticle synthesis for centuries. Nano-biotechnology aimed at the synthesis of nanomaterials, including silver nanoparticles, through utilization of biological media has acquired an auspicious role in science for human welfare. Despite recurrent nanoscale researches on physicochemical routes, coeval stages are predominated by greener methods in silver nanoparticle synthesis for the utilization of its inherent toxicity and exceedingly smaller sizes for biological and environmental applications. One of the principles of green routes for silver nanoparticle synthesis is reduction and stabilization via phytochemicals extracted from plants in a one-pot protocol of phytofunctionalization. Plants are preferred for their abundant availability, environmental non-toxicity and economical favorability and chiefly for the ease of aptness, unlike microbial pathways having tedious requirements of cellular culture maintenance conditions. The present work reviewed the most recent milestones set in the selection of types and parts of plants and optimized synthetic conditions employed in the fabrication of silver nanoparticles, in addition to quantitative and qualitative characterization. Furthermore, the use of phytofunctionalized silver nanoparticles for microbial growth inhibition and environmental remediation was also studied. Through the meticulous review of literature, potential applications were highlighted, which can provide researchers with a plethora of avenues for future investigations for remediation of the environment, in terms of both combating pathogenic microbes and environmental detoxification.