Yi-Zhi-Fang-Dai Formula Exerts a Protective Effect on the Injury of Tight Junction Scaffold Proteins in Vitro and in Vivo by Mediating Autophagy through Regulation of the RAGE/CaMKKβ/AMPK/mTOR Pathway
Author:
Affiliation:
1. Geriatrics Department of Chinese Medicine, Huadong Hospital, Fudan University
2. Department of Neurology, Renji Hospital, Shanghai Jiaotong University
3. Department of Chinese Medicine, East Hospital, Tongji University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/43/12/43_b20-00379/_pdf
Reference40 articles.
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3. 3) Chan Y, Chen W, Wan W, Chen Y, Li Y, Zhang C. Abeta1-42 oligomer induces alteration of tight junction scaffold proteins via RAGE-mediated autophagy in bEnd.3 cells. Exp. Cell Res., 369, 266–274 (2018).
4. 4) Kempuraj D, Mentor S, Thangavel R, Ahmed ME, Selvakumar GP, Raikwar SP, Dubova I, Zaheer S, Iyer SS, Zaheer A. Mast cells in stress, pain, blood–brain barrier, neuroinflammation and Alzheimer’s disease. Front. Cell. Neurosci., 13, 54 (2019).
5. 5) Coisne C, Engelhardt B. Tight junctions in brain barriers during central nervous system inflammation. Antioxid. Redox Signal., 15, 1285–1303 (2011).
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