Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease

Author:

Zhang Yong1,Wang Can2,Yu Bin1,Jiang Jian-Dong2,Kong Wei-Jia1

Affiliation:

1. Department of Virology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College

2. State Key Laboratory of Bioactive Natural Products and Function, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference36 articles.

1. 1) Masarone M, Rosato V, Dallio M, Abenavoli L, Federico A, Loguercio C, Persico M. Epidemiology and natural history of alcoholic liver disease. Rev. Recent Clin. Trials, 11, 167–174 (2016).

2. 2) Zhu B, Liu H, Liu L, Rong Y, Zang H, Liu W, You S, Xin S. Clinical characteristics of 4132 patients with alcoholic liver disease. Zhonghua Gan Zang Bing Za Zhi, 23, 680–683 (2015).

3. 3) Haseba T, Ohno Y. A new view of alcohol metabolism and alcoholism—role of the high-Km Class III alcohol dehydrogenase (ADH3). Int. J. Environ. Res. Public Health, 7, 1076–1092 (2010).

4. 4) Abenavoli L, Masarone M, Federico A, Rosato V, Dallio M, Loguercio C, Persico M. Alcoholic hepatitis: pathogenesis, diagnosis and treatment. Rev. Recent Clin. Trials, 11, 159–166 (2016).

5. 5) Zhan HD, Zhou HY, Sui YP, Du XL, Wang WH, Dai L, Sui F, Huo HR, Jiang TL. The rhizome of gastrodia elata blume—an ethnopharmacological review. J. Ethnopharmacol., 189, 361–385 (2016).

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