Chloroquine Improved Carbon Tetrachloride-Induced Liver Fibrosis through Its Inhibition of the Activation of Hepatic Stellate Cells: Role of Autophagy

Author:

He Wei1,Wang Bin2,Yang Jing1,Zhuang Yun1,Wang Liangzhi1,Huang Xiaodan3,Chen Jianping1

Affiliation:

1. Department of Gastroenterology, the Third Affiliated Hospital of Soochow University

2. Division of Nephrology, Huashan Hospital and Institute of Nephrology, Fudan University

3. Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference19 articles.

1. 1) Schuppan D, Afdhal NH. Liver cirrhosis. Lancet, 371, 838–851 (2008).

2. 2) Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol. Rev., 88, 125–172 (2008).

3. 3) Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell, 147, 728–741 (2011).

4. 4) Thoen LFR, Guimarães ELM, Dollé L, Mannaerts I, Najimi M, Sokal E, van Grunsven LA. A role for autophagy during hepatic stellate cell activation. J. Hepatol., 55, 1353–1360 (2011).

5. 5) Hernández-Gea V, Ghiassi-Nejad Z, Rozenfeld R, Gordon R, Fiel MI, Yue Z, Czaja MJ, Friedman SL. Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues. Gastroenterology, 142, 938–946 (2012).

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3