Evaluation of Interleukin-6 and Interleukin-10 in Patients with Urinary Tract Infection

Author:

Ahmed Hadi Dakheel ,Aseel Zghair Saadoon ,Ahmed abbas sahib

Abstract

Background: Urinary tract infection (UTIs) are considered to be the most common infections in humans.Aims: this study aimed to evaluate the immune status of the patients with UTI by studying of (IL-6 and IL-10).Subjects and Methods: A total of 49 UTI patients infected with gram –ve bacteria and 25 healthy controls were enrolled in this study. Urine samples from UTI cases was collected in AL-Imam AL-Hussain teaching hospital in Thi- Qar province, during the period from February 2014 to July 2014. Urinary isolates were identified by conventional methods.3 ml were collected in plastic tube and then centrifuged at 3000 round per minute (rpm) for 5 min to obtain sera. And after the serum sample were collected they were divided into two apendroff tubes and stored in deep freeze at – 20º C until performing IL-6 and IL-10. (Lewis et al., 2006).Results: Patients with E. coli infection accounted for 26 (53.06%); other culture results were as follows: 7 (14.29 %) patients had K. pneumonia, 9 (18.37%) patients had P. aerogenosa, 4 (8.16%) had Proteus and 3 (6.12%) patients had K.oxytoca. Measure levels of serum IL-6 and IL-10 for study group against control group, which is showed a significant increase (P ≤ 0.01) in the levels of interleukins (IL-6, IL-10) in all serum patients compared to the control group.Conclusion: E- coli was most common causative agent in UTI, The high rate concentration of IL-6 and IL-10 in patients with UTI compared with the healthy control group. This refers to the injury for their role in the immune response.

Publisher

Siree Journals

Subject

Drug Discovery,Pharmaceutical Science,Pharmacology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3