CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial

Author:

Gomez-Brouchet Anne1,Illac Claire1,Gilhodes Julia2,Bouvier Corinne3,Aubert Sébastien4,Guinebretiere Jean-Marc5,Marie Béatrice6,Larousserie Frédérique7,Entz-Werlé Natacha8,de Pinieux Gonzague910,Filleron Thomas2,Minard Véronique11,Minville Vincent12,Mascard Eric13,Gouin François1014,Jimenez Marta15,Ledeley Marie-Cécile16,Piperno-Neumann Sophie17,Brugieres Laurence10,Rédini Françoise10

Affiliation:

1. Department of Pathology, IUCT-Oncopole, CHU of Toulouse and University of Toulouse, Pharmacology and Structural Biology Institute, Toulouse, France

2. Biostatistics Unit, Claudius Regaud Institut, IUCT-Oncopole, Toulouse, France

3. Department of Pathology, CHU la Timone, Marseille, France

4. Department of Pathology, CHRU Lille, Lille, France

5. Department of Pathology, Curie Institut, Paris, France

6. Department of Pathology, CHU Nancy, Nancy, France

7. AP-HP, Hôpital Cochin, Service de Pathologie and Université Paris Descartes, Paris, France

8. Pediatric Oncology Department, Hautepierre, Strasbourg, France

9. Department of Pathology, CHU Tours, Tours, France

10. INSERM UMR1238, Université de Nantes, Nantes, France

11. Department of Children and Adolescents Oncology, Gustave Roussy Cancer Campus, Villejuif, France

12. Medical School of Rangueil, University Paul Sabatier, Toulouse, France

13. Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France

14. Department of Orthopedic Surgery, CHU Nantes, Nantes, France

15. Unicancer, Paris, France

16. Biostatistics Unit, Gustave Roussy Cancer Campus, Villejuif, France

17. Department of Medical Oncology, Curie Institut, Paris, France

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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